Histone H4 Products

Antibodies
Histone H4 Antibody
Histone H4 Antibody
Species: Hu, Mu, Rt, Xp
Applications: WB, DB, ICC/IF, IHC-P
Host: Rabbit Polyclonal
Histone H4 [ac Lys16] Antibod ...
Histone H4 [ac Lys16] Antibody
NB21-2077
Species: Hu, Mu, Rt, Ma
Applications: WB, DB, ICC/IF, ChIP (-)
Host: Rabbit Polyclonal
Kits
Lysates
Histone H4 Overexpression Lys ...
Histone H4 Overexpression Lysate (...
NBL1-11576
Applications: WB
Proteins
Histone H4 [Monomethyl Arg3] ...
Histone H4 [Monomethyl Arg3] Block...
NB21-2011PEP
Species: Hu
Histone H4 [Trimethyl Lys20] ...
Histone H4 [Trimethyl Lys20] Block...
NB21-2090PEP
Species: Hu
Histone H4 [Dimethyl Lys20] B ...
Histone H4 [Dimethyl Lys20] Blocki...
NB21-2089PEP
Species: Hu

Description

Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones. Methylation of position-specific lysine residues in histone N termini is a central modification for regulating epigenetic transitions in chromatin. Each methylatable lysine residue can exist in a mono, di, or tri methylated state. Arginine resdiues can also by mono or di methylated.

Bioinformatics

Entrez Human
Human
Human
Human
Mouse
Uniprot Human
Human
Human
Mouse
Rat
Product By Gene ID 121504
Alternate Names
  • HIST2H4
  • H4/E
  • H4FO
  • H4/D
  • H4FN
  • H4/C
  • H4FM
  • H4/B
  • H4FK
  • H4/A
  • H4FJ
  • histone H4
  • H4FI
  • HIST2H4B
  • H4FH
  • HIST2H4A
  • H4FG
  • HIST1H4L
  • H4FE
  • HIST1H4K
  • H4FD
  • HIST1H4J
  • H4FC
  • HIST1H4I
  • H4FB
  • HIST1H4H
  • H4FA
  • HIST1H4F
  • H4F2
  • HIST1H4E
  • H4/O
  • HIST1H4D
  • H4/N
  • HIST1H4C
  • H4/M
  • HIST1H4B
  • H4/K
  • HIST1H4A
  • H4/J
  • H4/p
  • H4/I
  • histone 4, H4
  • H4/H
  • MGC24116
  • H4/G
  • histone cluster 4, H4

Diseases related to Histone H4

Discover more about diseases related to Histone H4.

Stomach Neoplasms
Peritoneal Carcinomatosis
Malignant Neoplasm Of Stomach
Malignant Neoplasms
Neoplasms
Carcinomatosis

Pathways for Histone H4

View related products by pathway and learn more about each of the pathways below.

Cell Cycle
S Phase
G1 Phase

Research Areas for Histone H4

Find related products by research area and learn more about each of the different research areas below.

Chromatin Modifiers
Chromatin Research
DNA Repair
DNA replication, Transcription, Translation and Splicing
Epigenetics
HA Epitope Tags
Histones and Modified Histones
Phospho-Specific

PTMs for Histone H4

Learn more about PTMs related to Histone H4.

Phosphorylation

Bioinformatics Tool for Histone H4

Discover related pathways, diseases and genes to Histone H4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Histone H4 Blog Posts

Check out the latest blog posts on Histone H4.
H4 - Monitoring global chromatin structure through histone modifications
Histones make up the main protein component of chromatin and are responsible for storing and organizing the genome in a compact yet accessible manner. In addition to storage, histones play an important role in the regulation of various cellular pro...    Read more.
Histone H4 Phosphorylation: Affecting Liver Regeneration and Cancer
Histones are highly conserved proteins that function in the organization of nuclear DNA to create chromatin in eukaryotic cells. Post-translational alterations of histones are critical to monitoring and regulating DNA structure, expression, and gene t...    Read more.
Histone H4: Implications in Liver Cancer
Histones are highly conserved proteins that function in the organization of nuclear DNA to create chromatin in eukaryotic cells. Post-translational alterations of histones are critical to monitoring and regulating DNA structure, expression, and gene t...    Read more.
"Come Fly with Me" - New Drosophila Model Developed for Direct in Vivo Study of Histones
Forming the major protein component of chromatin, histones are essential to the structure and organization of chromosomes, forming the nucleosome around which DNA is packaged and wrapped.Antibody studies have revealed histones undergo various posttr...    Read more.
Read more Histone H4 related blogs.