Histone Deacetylase 4/HDAC4 Antibody (HDAC-144)

Product Discontinued

Histone Deacetylase 4/HDAC4 Antibody (HDAC-144) Summary

• Immunogen: Synthetic peptide: MSSQSHPDGLSGRDQPVEL, corresponding to amino acids 1-19 of Human HDAC4 conjugated to KLH with C-terminal added lysine.
• Localization: Cytoplasmic and Nuclear
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: HDAC4
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1-2 ug/ml
• Control:

  NIH 3T3 Whole Cell Lysate
  Histone Deacetylase 4/HDAC4 Overexpression Lysate

Reactivity Notes

Human, Mouse and Rat. Expected to cross-react with Chicken (100% identity with immunogen) due to sequence homology. Not yet tested in other species. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 10mM PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Concentration: 2 mg/ml
• Purity: Protein A or G purified

Alternate Names for Histone Deacetylase 4/HDAC4 Antibody (HDAC-144)

• HA6116
• HD4EC 3.5.1.98
• HDAC4
• HDAC-A
• HDACABDMR
• Histone Deacetylase 4
• histone deacetylase A
• KIAA0288AHO3

Background

Regulation of gene expression is mediated by several mechanisms, among them are DNA methylation, ATP-dependent chromatin remodeling, and posttranslational modifications of histones. These modifications include the dynamic acetylation and deacetylation of

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HDAC4
• Entrez:
  • 9759(Human)
  • 208727(Mouse)
  • 363287(Rat)
• Uniprot:
  • P56524(Human)