Guanylyl Cyclase beta 1 Antibody (SR2169) - BSA Free

Western Blot: Guanylyl Cyclase beta 1 Antibody (SR2169) [NBP3-21987] - Western blot analysis using NBP3-21987 in Human fetal brain lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: SR2169
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Guanylyl Cyclase beta 1 Antibody (SR2169) - BSA Free Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human Guanylyl Cyclase beta 1 (Uniprot #: Q02153)
• Specificity: Detects endogenous levels of total Guanylyl Cyclase beta 1
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: GUCY1B1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 71 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Guanylyl Cyclase beta 1 Antibody (SR2169) - BSA Free

• EC 4.6.1.2
• GC-SB3
• GCS-beta-1
• GCS-beta-3
• guanylate cyclase 1, soluble, beta 3
• guanylate cyclase soluble subunit beta-1
• Guanylate cyclase soluble subunit beta-3
• GUC1B3GUCB3
• GUCSB3GC-S-beta-1
• GUCY1B1
• Soluble guanylate cyclase small subunit

Background

Guanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GUCY1B1