Guanylyl Cyclase alpha 1 Antibody (SR2180) - BSA Free

Western Blot: Guanylyl Cyclase alpha 1 Antibody (SR2180) [NBP3-22388] - Western blot analysis using NBP3-22388 in Human fetal kidney lysate.

• Reactivity: Hu
• Applications: WB
• Clone: SR2180
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Guanylyl Cyclase alpha 1 Antibody (SR2180) - BSA Free Summary

• Description: Novus Biologicals Rabbit Guanylyl Cyclase alpha 1 Antibody (SR2180) - BSA Free (NBP3-22388) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human Guanylyl Cyclase alpha 1 (Uniprot #: Q02108)
• Specificity: Detects endogenous levels of total Guanylyl Cyclase alpha 1
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: GUCY1A1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 73 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Guanylyl Cyclase alpha 1 Antibody (SR2180) - BSA Free

• EC 4.6.1.2
• GC-S-alpha-1
• GCS-alpha-1
• GCS-alpha-3
• guanylate cyclase 1, soluble, alpha 3
• guanylate cyclase soluble subunit alpha-3
• Guanylyl Cyclase alpha 1
• GUC1A3
• GUC1A3GUCA3
• GUCSA3
• GUCSA3GC-SA3
• GUCY1A1
• GUCY1A3
• Soluble guanylate cyclase large subunit

Background

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GUCY1A1