Glut3 Antibody (202017) [Biotin]

• Applications: Flow, ICC/IF
• Clone: 202017
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Biotin
• Concentration: LYOPH

Glut3 Antibody (202017) [Biotin] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human Glut3
  Met1-Val496
  Accession # P11169
• Specificity: Detects human Glut3. Stains human Glut3-transfected NS0 and CHO cells, but not control transfectants. In flow cytometry, no cross‑reactivity with human Glut1 or Glut2 transfectants is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC2A3
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Glut3 belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane protein with 12 transmembrane domains. Glut3 is the glucose transporter responsible for maintaining an adequate glucose supply to neurons (1, 2). It is also expressed in placenta and articular chondrocytes (3, 4).

1. Vannuci, S.J. et al. (1997) Glia 21:2.
2. Mueckler, M. et al. (1997) Biochem. Soc. Trans. 25:951.
3. Illsley, N.P. (2000) Placenta 21:14.
4. Mobasheri, A. (2002) Cell Biol. Int. 26:297.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC2A3