GluR7/GRIK3 Antibody - BSA Free

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Western Blot: GluR7/GRIK3 Antibody [NBP1-76387] - Human brain tissue lysate with Glutamate receptor 7 antibody at (A) 1 and (B) 2 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

GluR7/GRIK3 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of the human Grik3. The immunogen is located within amino acids 30 - 80 of Grik3. Amino Acid Squence: EYADGPNAQVMNA
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRIK3
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Western Blot 1-2 ug/ml
Application Notes
Grik3 antibody can be used for detection of Grik3 by Western blot at 1 - 2 mg/ml.
Control Peptide
GluR7/GRIK3 Peptide (NBP1-76387PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for GluR7/GRIK3 Antibody - BSA Free

  • EAA5
  • Excitatory amino acid receptor 5
  • GLR7
  • GluK3
  • GluR7
  • gluR-7
  • GluR7a
  • GLUR7dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))
  • Glutamate receptor 7
  • glutamate receptor, ionotropic kainate 3
  • glutamate receptor, ionotropic, kainate 3
  • GRIK3

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik3, also known as glutamate receptor 7, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik3 is highly homologous to the related ionotrophic glutamate receptors Grik2 and Grik1. Grik3 has recently been shown to be an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses as grik3-null mice show significantly reduced short- and long-term synaptic potentiation. Other reports have suggested that different polymorphisms in the Grik3 protein may be associated with neurological defects such as recurrent major depressive disorder and schizophrenia. This Grik3 antibody does not cross-react with Grik2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GRIK3
Uniprot