Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody - BSA Free

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583] - Staining of human skeletal muscle shows low expression as expected.

Immunohistochemistry: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583] - Staining of human kidney shows strong cytoplasmic positivity in renal tubules.

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583] - Staining of human adrenal gland shows high expression.

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583] - Staining in human adrenal gland and skeletal muscle tissues using anti-GNS antibody. Corresponding GNS RNA-seq data are presented for the same tissues.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody - BSA Free (NBP2-38583) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: NYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTL
• Predicted Species: Mouse (94%), Rat (92%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GNS
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Glucosamine (N-acetyl)-6-Sulfatase/GNS Protein (NBP2-38583PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody - BSA Free

• EC 3.1.6
• EC 3.1.6.14
• G6Sglucosamine-6-sulfatase
• glucosamine (N-acetyl)-6-sulfatase
• Glucosamine6Sulfatase
• Glucosamine-6-Sulfatase
• GNS
• MGC21274
• N-acetylglucosamine-6-sulfatase

Background

The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNS
• Uniprot:
  • P15586()