Detects human, mouse, and rat GDF-8 in direct ELISAs and Western blots. In Western blots, this antibody shows approximately 30% cross-reactivity with recombinant human/mouse/rat GDF-11. In direct ELISAs, this antibody shows less than 1% cross-reactivity with recombinant mouse (rm) GDF-1, rmGDF-3, rmGDF-5, rmGDF-6, and rmGDF-9.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
GDF11
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for GDF-11/GDF-8 Antibody (84214) [Unconjugated]
GDF-11/GDF-8
Background
GDF-8, also known as Myostatin, belongs to the TGF-beta superfamily. It is synthesized as an inactive proprotein with the N-terminal pro-region and the C-terminal mature bioactive region. The GDF-8 proregion is capable of associating with active GDF-8 with high affinity and is a potent GDF-8 antagonist.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Publications for GDF-11/GDF-8 Antibody (MAB788)(9)
We have publications tested in 5 confirmed species: Human, Mouse, Rat, Chicken, Paralichthys olivaceus (Japanese Flounder).
We have publications tested in 2 applications: ELISA Development, Western Blot.
Bioinformatics Tool for GDF-11/GDF-8 Antibody (MAB788)
Discover related pathways, diseases and genes to GDF-11/GDF-8 Antibody (MAB788). Need help?
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