GDF-11/GDF-8 Antibody (84214) [Unconjugated]


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Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB

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GDF-11/GDF-8 Antibody (84214) [Unconjugated] Summary

Mouse myeloma cell line NS0-derived recombinant mouse GDF-8
Accession # O08689
Detects human, mouse, and rat GDF-8 in direct ELISAs and Western blots. In Western blots, this antibody shows approximately 30% cross-reactivity with recombinant human/mouse/rat GDF-11. In direct ELISAs, this antibody shows less than 1% cross-reactivity with recombinant mouse (rm) GDF-1, rmGDF-3, rmGDF-5, rmGDF-6, and rmGDF-9.
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1 ug/mL
Read Publications using
MAB788 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for GDF-11/GDF-8 Antibody (84214) [Unconjugated]

  • GDF-11/GDF-8


GDF-8, also known as Myostatin, belongs to the TGF-beta superfamily. It is synthesized as an inactive proprotein with the N-terminal pro-region and the C-terminal mature bioactive region. The GDF-8 proregion is capable of associating with active GDF-8 with high affinity and is a potent GDF-8 antagonist.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GDF-11/GDF-8 Antibody (MAB788)(9)

We have publications tested in 5 confirmed species: Human, Mouse, Rat, Chicken, Paralichthys olivaceus (Japanese Flounder).

We have publications tested in 2 applications: ELISA Development, Western Blot.

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ELISA Development
Western Blot
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Paralichthys olivaceus (Japanese Flounder)
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Showing Publications 1 - 9 of 9.
Publications using MAB788 Applications Species
J Liu, M Pan, D Huang, Y Guo, M Yang, W Zhang, K Mai Myostatin-1 Inhibits Cell Proliferation by Inhibiting the mTOR Signal Pathway and MRFs, and Activating the Ubiquitin-Proteasomal System in Skeletal Muscle Cells of Japanese Flounder Paralichthys olivaceus Cells, 2020;9(11):. 2020 [PMID: 33138208] (Western Blot, Paralichthys olivaceus (Japanese Flounder)) Western Blot Paralichthys olivaceus (Japanese Flounder)
C Pan, N Jaiswal Ag, Y Zulia, S Singh, K Sha, JL Mohler, KH Eng, J Chakkalaka, JJ Krolewski, KL Nastiuk Prostate tumor-derived GDF11 accelerates androgen deprivation therapy-induced sarcopenia JCI Insight, 2020;0(0):. 2020 [PMID: 32078585] (Western Blot, Mouse) Western Blot Mouse
O Miroshnych, WT Chang, JL Dragoo The Use of Platelet-Rich and Platelet-Poor Plasma to Enhance Differentiation of Skeletal Myoblasts: Implications for the Use of Autologous Blood Products for Muscle Regeneration Am J Sports Med, 2017;45(4):945-953. 2017 [PMID: 28027451] (Western Blot, Human) Western Blot Human
Lawlor M, Viola M, Meng H, Edelstein R, Liu F, Yan K, Luna E, Lerch-Gaggl A, Hoffmann R, Pierson C, Buj-Bello A, Lachey J, Pearsall S, Yang L, Hillard C, Beggs A Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C mice. Am J Pathol, 2014;184(6):1831-42. 2014 [PMID: 24726641] (Western Blot, Mouse) Western Blot Mouse
Lawlor MW, Read BP, Edelstein R, Yang N, Pierson CR, Stein MJ, Wermer-Colan A, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice. Am. J. Pathol., 2011;178(2):784-93. 2011 [PMID: 21281811] (Western Blot, Mouse) Western Blot Mouse
Yamada M, Tatsumi R, Yamanouchi K, Hosoyama T, Shiratsuchi S, Sato A, Mizunoya W, Ikeuchi Y, Furuse M, Allen RE High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite cell quiescence in vivo. Am. J. Physiol., Cell Physiol., 2010;298(3):C465-76. 2010 [PMID: 20007454] (Western Blot, Rat) Western Blot Rat
Sengle G, Ono RN, Lyons KM, Bachinger HP, Sakai LY A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J. Mol. Biol., 2008;381(4):1025-39. 2008 [PMID: 18621057] (ELISA Development, Human) ELISA Development Human
Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bachinger HP, Sakai LY Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J. Biol. Chem., 2008;283(20):13874-88. 2008 [PMID: 18339631] (Western Blot, Human) Western Blot Human
Sato F, Kurokawa M, Yamauchi N, Hattori MA Gene silencing of myostatin in differentiation of chicken embryonic myoblasts by small interfering RNA. Am. J. Physiol., Cell Physiol., 2006;291(3):C538-45. 2006 [PMID: 16611734] (Western Blot, Chicken) Western Blot Chicken

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Gene Symbol GDF11