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GDF-11/GDF-8 Products

Antibodies
GDF-11/GDF-8 Antibody (743835 ...
GDF-11/GDF-8 Antibody (743835R) [U...
MAB19582R
1958-GD) induces hemoglobin expression in the K562 human chronic myelogenous leukemia cell line in a dose-dependent manner (orange line), as measured by the pseudoperoxidase assay. Induction of hemoglobin expression by GDF-11/BMP-11 (25 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human GDF-11/GDF-8 Monoclonal Antibody (Catalog # MAB19582R). The ND50 is typically 0.04-0.2 µg/mL. This antibody also neutralizes GDF-8 in a similar K562 bioassay." class="big_lightbox" target="_blank"> Neutralization GDF-11/GDF-8 Antibody (743835R) [Unconjugated]
MAB19584) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human GDF-11/GDF-8 Monoclonal Antibody (Catalog # MAB19582R) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994)." class="big_lightbox" target="_blank"> ELISA GDF-11/GDF-8 Antibody (743835R) [Unconjugated]
Species: Hu
Applications: ELISA, B/N
Host: Mouse Monoclonal
GDF-11/GDF-8 Antibody (743835 ...
GDF-11/GDF-8 Antibody (743835) [Un...
MAB19582
1958-GD) induces hemoglobin expression in the K562 human chronic myelogenous leukemia cell line in a dose-dependent manner (orange line), as measured by the pseudoperoxidase assay. Induction of hemoglobin expression by GDF-11/BMP-11 (25 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human GDF-11/GDF-8 Monoclonal Antibody (Catalog # MAB19582). The ND50 is typically 0.04-0.2 µg/mL. This antibody also neutralizes GDF-8 in a similar K562 bioassay." class="big_lightbox" target="_blank"> Neutralization GDF-11/GDF-8 Antibody (743835) [Unconjugated]
MAB19584) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human GDF-11/GDF-8 Monoclonal Antibody (Catalog # MAB19582) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994)." class="big_lightbox" target="_blank"> ELISA GDF-11/GDF-8 Antibody (743835) [Unconjugated]
Species: Hu
Applications: ELISA, B/N
Host: Mouse Monoclonal

Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]

Bioinformatics

Product By Gene ID 10220
Alternate Names
  • BMP11
  • BMP-11
  • bone morphogenetic protein 11
  • GDF-11
  • growth/differentiation factor 11
  • VHO