GDF-11/GDF-8 Products

Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]

Bioinformatics

Product By Gene ID	10220
Alternate Names	BMP11 BMP-11 bone morphogenetic protein 11 GDF-11 growth/differentiation factor 11 VHO