GDF-11/GDF-8 Antibody (743835R) [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: ELISA, B/N
• Clone: 743835R
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

GDF-11/GDF-8 Antibody (743835R) [mFluor Violet 450 SE] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: E. coli-derived recombinant human GDF-11/GDF-8
  Asn299-Ser407
  Accession # O95390
• Specificity: Detects human GDF-11/GDF-8 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA
  • Neutralization
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from cell culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for GDF-11/GDF-8 Antibody (743835R) [mFluor Violet 450 SE]

• BMP11
• BMP-11
• bone morphogenetic protein 11
• GDF-11
• GDF-11/GDF-8
• growth/differentiation factor 11
• VHO

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.