GABA-AR alpha 1 Antibody - BSA Free

Western Blot: GABA-AR alpha 1 Antibody [NBP2-16565] - GABA A Receptor alpha 1 antibody detects GABA A Receptor alpha 1 protein by Western blot analysis. Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with GABA A Receptor alpha 1 antibody diluted by 1:500.

Immunohistochemistry-Paraffin: GABA-A R alpha 1 Antibody [NBP2-16565] - Paraffin-embedded rat brain. GABA A Receptor alpha 1 antibody [N1C1] diluted at 1:500.

Immunohistochemistry-Paraffin: GABA-A R alpha 1 Antibody [NBP2-16565] - Paraffin-embedded rat brain. GABA A Receptor alpha 1 antibody [N1C1] diluted at 1:500.

• Reactivity: Hu, Rt, Mu, Bv, Ch, Rb, RM
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

GABA-AR alpha 1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit GABA-AR alpha 1 Antibody - BSA Free (NBP2-16565) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GABA-AR alpha 1. The exact sequence is proprietary.
• Localization: Cell junction; synapse; postsynaptic cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein
• Predicted Species: Mouse (99%), Rhesus Macaque (100%), Bovine (100%), Rabbit (100%), Chicken (97%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GABRA1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 52 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Zebrafish (89%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 20% Glycerol
• Preservative: 0.025% Proclin 300
• Purity: Antigen Affinity-purified

Alternate Names for GABA-AR alpha 1 Antibody - BSA Free

• ECA4
• EJM
• EJM5GABA(A) receptor subunit alpha-1
• GABA A R alpha 1
• GABAAR alpha 1
• GABAARa1
• GABRA1
• gamma-aminobutyric acid (GABA) A receptor, alpha 1
• gamma-aminobutyric acid receptor subunit alpha-1

Background

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: GABRA1
• Uniprot:
  • P14867(Human)