GABA-A R gamma 2 Antibody


Western Blot: GABA-A R gamma 2 Antibody [NB300-190] - Mouse whole brain lysate showing specific immunolabeling of the ~46 kDa gamma-2-subunit of GABAa -R.
Immunohistochemistry: GABA-A R gamma 2 Antibody [NB300-190] - Immunostaining of mouse retina showing specific labeling of the GABAa gamma-2 subunit in green, calbindin in red and DNA in blue. Photo courtesy of Dr. more

Product Details

Reactivity Hu, Mu, Rt, Bv, Ca, Ch, PmSpecies Glossary
Applications WB, IHC, KD
0.15 mg/ml

Order Details

GABA-A R gamma 2 Antibody Summary

Fusion protein from the cytoplasmic loop of the gamma 2 subunit. Accession # P18508
Specific for the ~46k gamma2-subunit of the GABAA receptor in Western blots.
Predicted Species
Bovine (100%), Chicken (100%), Canine (100%), Primate (100%). Backed by our 100% Guarantee.
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunohistochemistry 1:100
  • Knockdown Validated
  • Western Blot 1:1000
Application Notes
Use in Immunohistochemistry reported in scientific literature (PMID 25716832). Knockdown validation (PMID: 31747610).
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using
NB300-190 in the following applications:

  • IHC
    2 publications
  • KD
    1 publication
  • WB
    9 publications

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID:32732906). Mouse reactivity reported in scientific literature (PMID: 23922756). Human reactivity reported in scientific literature (PMID: 24668190).

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
No Preservative
0.15 mg/ml
Antigen Affinity-purified

Alternate Names for GABA-A R gamma 2 Antibody

  • CAE2
  • ECA2
  • GABA A R gamma 2
  • GABA(A) receptor subunit gamma-2
  • GABAAR gamma 2
  • GABAARg2
  • GABRG2
  • gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • gamma-aminobutyric acid receptor subunit gamma-2
  • GEFSP3


GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GABA-A R gamma 2 Antibody (NB300-190)(15)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 3 applications: IHC, KD, WB.

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Showing Publications 1 - 10 of 15. Show All 15 Publications.
Publications using NB300-190 Applications Species
Chan ES, Ge Y, So YW et al. Allosteric potentiation of GABAA receptor single-channel conductance by netrin-1 during neuronal-excitation-induced inhibitory synaptic homeostasis Cell reports Nov 1 2022 [PMID: 36323250] (WB, Mouse) WB Mouse
Janach G, BOhm M, DOhne N et al. Interferon-gamma enhances neocortical synaptic inhibition by promoting membrane association and phosphorylation of GABAA receptors in a protein kinase C-dependent manner Brain, Behavior, and Immunity Jan 1 2022 [PMID: 34998939] (WB, Rat) WB Rat
He Y, Cai X, Liu H Et Al. 5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding Molecular psychiatry Jul 21 2021 [PMID: 34290371]
Kim ER, Xu Y, Cassidy RM et al. Paraventricular hypothalamus mediates diurnal rhythm of metabolism Nat Commun Jul 30 2020 [PMID: 32732906] (IHC, Mouse) IHC Mouse
Shimell JJ, Shah BS, Cain SM et al. The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation Cell Rep Nov 19 2019 [PMID: 31747610] (KD, Human, Mouse, Rat) KD Human, Mouse, Rat
Fan J, Li D, Chen HS et al. Metformin Produces Anxiolytic-like Effects in Rats by Facilitating GABAA Receptor Trafficking to Membrane. Br. J. Pharmacol. Oct 14 2018 [PMID: 30318707] (WB, Rat) WB Rat
Huang S, Hokenson K, Bandyopadhyay S et al. Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex. J. Neurosci. 2015 Dec 02 [PMID: 26631472] (WB, Mouse) WB Mouse
Johnson AC, Nagle KJ, Tremble SM, Cipolla MJ. The Contribution of Normal Pregnancy to Eclampsia. PLoS ONE. 2015 Jul 29 [PMID: 26218425] (WB, Rat) WB Rat
Wu Z, Kim ER, Sun H et al. GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding J. Neurosci. 2015 Feb 25 [PMID: 25716832] (IHC, Mouse) IHC Mouse
Fatemi SH, Reutiman TJ, Folsom TD et al. Downregulation of GABAA Receptor Protein Subunits alpha6, beta2, delta, epsilon, gamma2, theta, and p2 in Superior Frontal Cortex of Subjects with Autism. J Autism Dev Disord 2014 Mar 26 [PMID: 24668190] (WB, Human) WB Human
Show All 15 Publications.

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FAQs for GABA-A R gamma 2 Antibody (NB300-190). (Showing 1 - 1 of 1 FAQs).

  1. I am looking for a "Primary antibody for GABAa receptor gamma 2" raised from antigen whose aa sequence is between exon 5-10. The application will be for "Immunohistochemistry". I would like to know if you have a product to match it?
    • NB300-190 is direceted against GABA A receptor gamma 2, is suitable for use in IHC and uses a fusion protein from the cytoplasmic loop of the gamma 2 subunit as an antigen, so this should suit your needs.

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Gene Symbol GABRG2