100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol.
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified
Immunoprecipitation 15 ug ** ** 68% of all GABA-A receptors in dodecylsulfate extracts of rat forebrains (150 ul) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reactivity Mouse reactivity reported in scientific literature (PMID: 16807363). It is anticipated that the antibody will react with canine, human and non-human primate based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
Alternate Names for GABA-A R beta 2 Antibody
GABA(A) receptor subunit beta-2
GABAAR beta 2
gamma-aminobutyric acid (GABA) A receptor, beta 2
gamma-aminobutyric acid A receptor beta 2
gamma-aminobutyric acid receptor subunit beta-2
GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for GABA-A R beta 2 Antibody (NB300-198). (Showing 1 - 1 of 1 FAQs).
Could you please provide the immunogen sequence for Anti-GABA A Receptor beta 3 antibody and Anti-GABA A Receptor beta 2 antibody, catalog number NB300-199 and NB300-198 at your earliest convenience? If the exact sequence is not available, could you please tell me a broader range of amino acids or the region of the peptide from which it is derived? Also, please let me know if this information can be made public. Thank you for your help in this matter.
The immunogen for NB300-199 falls within 340-420 amino acids, while the immunogen for NB300-198 falls within the range of 327-451.