GABA-AR alpha 5 Antibody

Images

 
Western Blot: GABA-A R alpha 5 Antibody [NB300-195] - Mouse whole brain showing specific immunolabelling of the ~55kDa alpha 5-subunit of the GABAA R.

Product Details

Summary
Reactivity Mu, Rt, Hu, Bv, Ca, Ch, Pm, ZeSpecies Glossary
Applications WB, IHC, IHC-FrFl
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

GABA-AR alpha 5 Antibody Summary

Immunogen
Fusion protein from the cytoplasmic loop of the alpha 5 subunit of rat GABAA receptor.
Specificity
Specific for endogenous levels of the ~55k alpha 5-subunit of the GABAA receptor.
Predicted Species
Human (100%), Zebrafish (100%), Canine (100%), Bovine (100%), Primate (100%), Chicken (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GABRA5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • Immunohistochemistry
  • Immunohistochemistry Free-Floating
Application Notes
Use in Immunohistochemistry reported in scientific literature (PMID: 28352479). Use in Immunohistochemistry-free floating reported in scientific literature (PMID: 26322928).
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NB300-195 in the following applications:

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for GABA-AR alpha 5 Antibody

  • GABA A R alpha 5
  • GABA(A) receptor subunit alpha-5
  • GABAAR alpha 5
  • GABAARa5
  • GABRA5
  • gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • gamma-aminobutyric acid receptor subunit alpha-5
  • MGC138184

Background

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GABA-AR alpha 5 Antibody (NB300-195)(5)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GABRA5
Entrez
Uniprot