FMO3 Antibody - BSA Free

Western Blot: FMO3 Antibody [NBP1-33583] - Sample (30 ug of whole cell lysate) A: H1299 7. 5% SDS PAGE; antibody diluted at 1:1000.

Immunocytochemistry/Immunofluorescence: FMO3 Antibody [NBP1-33583] - Analysis of methanol-fixed A431, using antibody at 1:200 dilution.

Immunohistochemistry-Paraffin: FMO3 Antibody [NBP1-33583] - Paraffin-embedded OVCAR3 xenograft, using antibody at 1:100 dilution.

Western Blot: FMO3 Antibody [NBP1-33583] - Sample (50 ug of whole cell lysate) A: Mouse liver 7. 5% SDS PAGE; antibody diluted at 1:1000.

• Reactivity: Hu, Mu, Pm, RM
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

FMO3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit FMO3 Antibody - BSA Free (NBP1-33583) is a polyclonal antibody validated for use in IHC, WB and ICC/IF. Anti-FMO3 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human FMO3. The exact sequence is proprietary.
• Localization: Microsome membrane, Endoplasmic reticulum membrane
• Predicted Species: Rhesus Macaque (100%), Chimpanzee (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FMO3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 60 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rat (81%), Canine (84%), Rabbit (81%), Bovine (83%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for FMO3 Antibody - BSA Free

• dimethylaniline monooxygenase [N-oxide-forming] 3
• Dimethylaniline oxidase 3
• dJ127D3.1
• EC 1.14.13.8
• flavin containing monooxygenase 3
• FMO 3
• FMO form 2
• FMO II
• FMOII
• Hepatic flavin-containing monooxygenase 3
• hepatic flavin-containing monooxygenase-3
• MGC34400
• TMAU

Background

The mammalian flavin-containing monooxygenases (FMO; EC 1.14.13.8) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme (Ziegler, 1990 [PubMed 2203193]; Hines et al., 1994 [PubMed 8128486]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for FMO3 Antibody (NBP1-33583)(1)

Publication using NBP1-33583

• Chen LW, Chen PH, Yen JH. Inhibiting adipose tissue M1 cytokine expression decreases DPP4 activity and insulin resistance in a type 2 diabetes mellitus mouse model PLOS ONE 2021-05-27 [PMID: 34043673]

Bioinformatics

• Gene Symbol: FMO3