FMO2 Antibody

Images

 
Western Blot: FMO2 Antibody [NBP1-33318] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: FMO2 Antibody [NBP1-33318] - Paraffin-embedded A549 xenograft, using antibody at 1:500 dilution.

Product Details

Summary
Reactivity Hu, Pm, RMSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

FMO2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human FMO2. The exact sequence is proprietary.
Localization
Microsome membrane, Endoplasmic reticulum membrane
Predicted Species
Rhesus Macaque (96%), Primate (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FMO2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chimpanzee (99%), Bovine (81%), Mouse (83%), Rat (82%), Rabbit (84%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FMO2 Antibody

  • dimethylaniline monooxygenase [N-oxide-forming] 2
  • Dimethylaniline oxidase 2
  • EC 1.14.13.8
  • flavin containing monooxygenase 2 (non-functional)
  • flavin containing monooxygenase 2
  • FLJ40826
  • FMO 1B1
  • FMO 2
  • FMO, pulmonary
  • FMO1B1
  • Pulmonary flavin-containing monooxygenase 2

Background

The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol FMO2