FMO3 Products

Description

The mammalian flavin-containing monooxygenases (FMO; EC 1.14.13.8) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme (Ziegler, 1990 [PubMed 2203193]; Hines et al., 1994 [PubMed 8128486]).[supplied by OMIM]

Bioinformatics

Entrez	2328 Human
Uniprot	AAH32016.1 Human NP_001002294 Human NP_008825 Human P31513 Human
Product By Gene ID	2328
Alternate Names	dimethylaniline monooxygenase [N-oxide-forming] 3 Dimethylaniline oxidase 3 dJ127D3.1 EC 1.14.13.8 flavin containing monooxygenase 3 FMO 3 FMO form 2 FMO II FMOII Hepatic flavin-containing monooxygenase 3 hepatic flavin-containing monooxygenase-3 MGC34400 TMAU