Fes Antibody - BSA Free

Staining of human Placenta shows moderate cytoplasmic positivity in trophoblastic cells.

Staining of human Skeletal muscle shows no cytoplasmic positivity in myocytes as expected.

Staining of human Bone marrow shows strong cytoplasmic positivity in hematopoietic cells.

Staining of human Kidney shows strong cytoplasmic positivity in cells in tubules.

• Reactivity: Hu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Fes Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Fes Antibody - BSA Free (NBP1-83429) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: DSAQAKRKYQEASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRAAQLHHQHHHQLLLPGLLRSLQDLHEEMACILKEILQEYLEISSLVQDEVVAIHREMAAAAARIQPEAEYQGFLRQYGSAPDVPPCVTFDESLLEEGEPLEP
• Predicted Species: Rat (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FES
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Fes Protein (NBP1-83429PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Fes Antibody - BSA Free

• EC 2.7.10
• EC 2.7.10.2
• feline sarcoma oncogene
• feline sarcoma virus
• Fes
• FPS
• Proto-oncogene c-Fes
• Proto-oncogene c-Fps
• proto-oncogene tyrosine-protein kinase Fes/Fps
• tyrosine-protein kinase Fes/Fps

Background

FES (FES feline sarcoma oncogene) has tyrosine-specific protein kinase activity which is required for cellular transformation maintenance. FES plays a role in regulation of cell attachment, cell spreading, cell differentiation and microtubule assembly as well as being involved in cell scattering. FES is known to have interactions with ERZ, NSF, EGFR, CSF2RB and RASA1. This protein is currently being studied for research on the following diseases and disorders: sarcoma, leukemia, colon cancer, neuronitis, hemangioma and hematopoiesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FES