Fc gamma RIIIB/CD16b Antibody (MM0272-5L11) [Biotin]

Product Discontinued

Fc gamma RIIIB/CD16b Antibody (MM0272-5L11) [Biotin] Summary

• Description: This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
• Immunogen: Human CD16b
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCGR3B
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for Fc gamma RIIIB/CD16b Antibody (MM0272-5L11) [Biotin]

• CD16
• CD16b antigen
• CD16b
• Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
• Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
• Fc gamma RIIIB
• FCG3
• Fc-gamma receptor IIIb (CD 16)
• Fc-gamma RIII
• Fc-gamma RIIIb
• Fc-gamma RIII-beta
• FCGR3
• FCGR3B
• FcgRIIIB
• FcR-10
• fcRIII
• FCRIIIB
• IGFR3
• IgG Fc receptor III-1
• low affinity immunoglobulin gamma Fc region receptor III-B

Background

CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCGR3B