Fc gamma RIIIB/CD16b Antibody (MM0272-5L11) [Alexa Fluor® 488]

Product Discontinued

Fc gamma RIIIB/CD16b Antibody (MM0272-5L11) [Alexa Fluor® 488] Summary

• Immunogen: Human CD16b
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCGR3B
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Fc gamma RIIIB/CD16b Antibody (MM0272-5L11) [Alexa Fluor® 488]

• CD16
• CD16b antigen
• CD16b
• Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
• Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
• Fc gamma RIIIB
• FCG3
• Fc-gamma receptor IIIb (CD 16)
• Fc-gamma RIII
• Fc-gamma RIIIb
• Fc-gamma RIII-beta
• FCGR3
• FCGR3B
• FcgRIIIB
• FcR-10
• fcRIII
• FCRIIIB
• IGFR3
• IgG Fc receptor III-1
• low affinity immunoglobulin gamma Fc region receptor III-B

Background

CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCGR3B