Fc gamma RIII (CD16) Antibody (245536) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
245536
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Fc gamma RIII (CD16) Antibody (245536) [Unconjugated] Summary

Immunogen
Raised against Fc gamma RIII (CD16).
Source
N/A
Clonality
Monoclonal
Host
Mouse
Gene
FCGR3B
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 2.5 ug/10^6 cells
  • CyTOF-ready
Publications
Read Publications using
MAB2546 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Fc gamma RIII (CD16) Antibody (245536) [Unconjugated]

  • CD16
  • CD16A
  • Fc fragment of IgG receptor IIIa
  • Fc gamma RIII
  • FCG3
  • FCGR3
  • FcgRIII
  • FCR-10
  • FCRIII
  • FCRIIIA
  • IGFR3
  • IMD20

Background

Fc gamma RIIIA and B are low affinity receptors for polyvalent immune-complexed IgG. Fc gamma RIIIA is a transmembrane activating receptor expressed by NK cells, T cells, monocytes, and macrophages. Fc gamma RIIIB is a non-activating GPI-linked decoy receptor expressed on neutrophils and eosinophils.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Fc gamma RIII (CD16) Antibody (MAB2546)(6)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: Flow, Functional Assay, IP.


Filter By Application
Flow
(4)
Functional Assay
(1)
IP
(1)
All Applications
Filter By Species
Human
(6)
All Species
Showing Publications 1 - 6 of 6.
Publications using MAB2546 Applications Species
KO Dixon, J O'Flynn, N Klar-Moham, MR Daha, C van Kooten Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-? Eur. J. Immunol, 2017;0(0):. 2017 [PMID: 28105653] (Flow,, Human) Flow Human
Evidence for chemokine synergy during neutrophil migration in ARDS Thorax, 2016;0(0):. 2016 [PMID: 27496101] (Flow,, Human) Flow Human
Chauhan A, Moore T, Bi Y, Chen C FcgammaRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression. J Biol Chem, 2016;291(3):1368-86. 2016 [PMID: 26582197] (Flow,, Human) Flow Human
Chauhan A, Chen C, Moore T, DiPaolo R Induced expression of FcgammaRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-gammahigh subset. J Biol Chem, 2015;290(8):5127-40. 2015 [PMID: 25556651] (Flow,, Human) Flow Human
Mou, Xiao, Zhou, Yuepeng, Jiang, Peng, Zhou, Tong, Jiang, Qian, Xu, Chengche, Liu, Hongli, Zheng, Tingting, Yuan, Guoyue, Zhang, Yanyun, Chen, Deyu, Mao, Chaoming The regulatory effect of UL-16 binding protein-3 expression on the cytotoxicity of NK cells in cancer patients. Sci Rep, 2014;4(0):6138. 2014 [PMID: 25138242] (Functional Assay,, Human) Functional Assay Human
Chauhan AK, Moore TL Immune complexes and late complement proteins trigger activation of Syk tyrosine kinase in human CD4(+) T cells. Clin. Exp. Immunol., 2012;167(2):235-45. 2012 [PMID: 22235999] (IP,, Human) IP Human

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Bioinformatics

Gene Symbol FCGR3B
Entrez
Uniprot