ERAB Antibody (SR1440) - BSA Free

Western Blot: ERAB Antibody (SR1440) [NBP3-21757] - Western blot analysis using NBP3-21757 in HeLa cell lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF, IHC
• Clone: SR1440
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ERAB Antibody (SR1440) - BSA Free Summary

• Description: Novus Biologicals Rabbit ERAB Antibody (SR1440) - BSA Free (NBP3-21757) is a recombinant monoclonal antibody validated for use in IHC, WB, Flow and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human ERAB (Uniprot #: Q99714)
• Specificity: Detects endogenous levels of total ERAB
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: HSD17B10
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:50
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:1000-1:5000
• Theoretical MW: 27 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ERAB Antibody (SR1440) - BSA Free

• 17-beta-HSD 10
• 17-beta-hydroxysteroid dehydrogenase 10
• 17b-HSD10
• 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
• ABAD
• amyloid-beta peptide binding alcohol dehydrogenase
• CAMR
• DUPXp11.22
• EC 1.1.1.178
• EC 1.1.1.35
• Endoplasmic reticulum-associated amyloid beta-peptide-binding protein
• ERAB3-hydroxyacyl-CoA dehydrogenase type-2
• HADH2AB-binding alcohol dehydrogenase
• hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme Adehydrogenase, type II
• hydroxysteroid (17-beta) dehydrogenase 10
• mental retardation, X-linked, syndromic 10
• MHBD
• Mitochondrial ribonuclease P protein 2,3-hydroxyacyl-CoA dehydrogenase type II
• Mitochondrial RNase P protein 2
• MRPP2HCD2
• MRX17
• MRX31
• MRXS10
• SCHAD
• SDR5C1
• short chain dehydrogenase/reductase family 5C, member 1
• short chain L-3-hydroxyacyl-CoA dehydrogenase type 2
• short chain type dehydrogenase/reductase XH98G2
• Short-chain type dehydrogenase/reductase XH98G2
• Type II HADH
• XH98G2

Background

ERAB encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HSD17B10