ERAB Antibody (OTI10B4)

Images

 
Western Blot: ERAB Antibody (10B4) [NBP2-02118] Analysis of extracts (35ug) from 9 different cell lines by using anti-ERAB monoclonal antibody.
Immunocytochemistry/ Immunofluorescence: ERAB Antibody (10B4) [NBP2-02118] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY ERAB.
Immunohistochemistry-Paraffin: ERAB Antibody (10B4) [NBP2-02118] - Staining of paraffin-embedded pancreas tissue using anti-ERABmouse monoclonal antibody.
Flow Cytometry: ERAB Antibody (10B4) [NBP2-02118] - Analysis of Hela cells, using anti-ERAB antibody, (Red) compared to a nonspecific negative control antibody (Blue).
Western Blot: ERAB Antibody (10B4) [NBP2-02118] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ERAB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ...read more
Immunohistochemistry-Paraffin: ERAB Antibody (10B4) [NBP2-02118] - Staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-ERAB mouse monoclonal antibody.
Immunohistochemistry-Paraffin: ERAB Antibody (10B4) [NBP2-02118] - Staining of paraffin-embedded Carcinoma of liver tissue using anti-ERAB mouse monoclonal antibody.
Immunohistochemistry-Paraffin: ERAB Antibody (10B4) [NBP2-02118] - Staining of paraffin-embedded Kidney tissue using anti-ERAB mouse monoclonal antibody.
Immunohistochemistry-Paraffin: ERAB Antibody (10B4) [NBP2-02118] - Staining of paraffin-embedded liver tissue using anti-ERABmouse monoclonal antibody.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
Clone
OTI10B4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

ERAB Antibody (OTI10B4) Summary

Immunogen
Full length human recombinant protein of human HSD17B10(NP_004484) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HSD17B10
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50
Theoretical MW
26.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBP2-02118.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ERAB Antibody (OTI10B4)

  • 17-beta-HSD 10
  • 17-beta-hydroxysteroid dehydrogenase 10
  • 17b-HSD10
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • ABAD
  • amyloid-beta peptide binding alcohol dehydrogenase
  • CAMR
  • DUPXp11.22
  • EC 1.1.1.178
  • EC 1.1.1.35
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein
  • ERAB3-hydroxyacyl-CoA dehydrogenase type-2
  • HADH2AB-binding alcohol dehydrogenase
  • hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme Adehydrogenase, type II
  • hydroxysteroid (17-beta) dehydrogenase 10
  • mental retardation, X-linked, syndromic 10
  • MHBD
  • Mitochondrial ribonuclease P protein 2,3-hydroxyacyl-CoA dehydrogenase type II
  • Mitochondrial RNase P protein 2
  • MRPP2HCD2
  • MRX17
  • MRX31
  • MRXS10
  • SCHAD
  • SDR5C1
  • short chain dehydrogenase/reductase family 5C, member 1
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2
  • short chain type dehydrogenase/reductase XH98G2
  • Short-chain type dehydrogenase/reductase XH98G2
  • Type II HADH
  • XH98G2

Background

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ERAB Antibody (NBP2-02118)(1)


Showing Publication 1 - 1 of 1.
Publication using NBP2-02118 Applications Species
Halbert D, Domenyuk V, Spetzler D et al. Aptamers and uses thereof United States Patent Application US 9958448 B2 2018

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for ERAB Antibody (NBP2-02118) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-70871AF350
Alexa Fluor 405 NBP2-70871AF405
Alexa Fluor 488 NBP2-70871AF488
Alexa Fluor 532 NBP2-70871AF532
Alexa Fluor 594 NBP2-70871AF594
Alexa Fluor 647 NBP2-70871AF647
Alexa Fluor 700 NBP2-70871AF700
Alexa Fluor 750 NBP2-70871AF750
Allophycocyanin NBP2-70871APC
Biotin NBP2-70871B
DyLight 350 NBP2-70871UV
DyLight 405 NBP2-70871V
DyLight 488 NBP2-70871G
DyLight 550 NBP2-70871R
DyLight 594 NBP2-70871DL594
DyLight 650 NBP2-70871C
DyLight 680 NBP2-70871FR
DyLight 755 NBP2-70871IR
FITC NBP2-70871F
HRP NBP2-70871H
Janelia Fluor 549 NBP2-70871JF549
Janelia Fluor 646 NBP2-70871JF646
PE NBP2-70871PE
PerCP NBP2-70871PCP

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Bioinformatics

Gene Symbol HSD17B10
Entrez