EML4 Antibody [DyLight 550]

• Reactivity: Hu
• Applications: IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 550

EML4 Antibody [DyLight 550] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 931 and 981of human echinoderm microtubule associated protein like 4 using the numbering given in entry NP_061936.2 (GeneID 27436).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EML4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for EML4 Antibody [DyLight 550]

• C2orf2
• echinoderm microtubule associated protein like 4
• echinoderm microtubule-associated protein-like 4
• ELP120
• EMAP-4
• EMAPL4
• FLJ10942
• FLJ32318
• Restrictedly overexpressed proliferation-associated protein
• Ropp 120
• ROPP120DKFZp686P18118

Background

Echinoderm microtubule associated protein like 4 (EML4) has been identified as part of a gene fusion with the kinase domain of the anaplastic lymphoma receptor tyrosine kinase (ALK) in non-small cell lung cancer. EML4 associates with in vitro polymerized microtubules. In the cell, phosphorylated EML4 associates with the mitotic spindle and is essential for proliferation and microtubule network formation. Alternative names for EML4 include EMAPL4, ropp120, C2orf2, ELP120, and EMAP-4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EML4