EDNRB/Endothelin R Type B Antibody

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

EDNRB/Endothelin R Type B Antibody Summary

Immunogen
A synthetic peptide from the c-terminal of human Endothelin B receptor (EDNRB) conjugated to an immunogenic carrier protein was used as the immunogen. The peptide is homologous in rat and mouse.
Specificity
Appears to be specific for EDNRB.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EDNRB
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 10-50 ug/ml
  • Immunohistochemistry 10-50 ug/ml
  • Immunohistochemistry-Paraffin 10-50 ug/ml
Application Notes
WB. A concentration of 10-50 ug/ml is recommended. The optimal concentration should be determined by the end user. Although not confirmed, this antibody may be useful in IHC-Paraffin/Frozen. Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 25572612)
The sample size is shipped in liquid form.
Publications
Read Publications using
NBP1-30599 in the following applications:

  • 1 publication
  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
No buffer
Preservative
No Preservative
Concentration
LYOPH
Purity
IgG purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized water.

Alternate Names for EDNRB/Endothelin R Type B Antibody

  • ABCDS
  • EDNRB
  • endothelin B receptor
  • Endothelin receptor non-selective type
  • endothelin receptor type B
  • ETB
  • ET-B
  • ETBR
  • ET-BR
  • ETRB
  • HSCR
  • HSCR2
  • WS4A

Background

Endothelin receptor type B (ETRB) is a G protein-coupled receptor that activates a phosphatidylinoitol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. A splice variant (SVR), differing in the intracellular C-terminal domain, has been described for this receptor. Both WT and the variant bind ET1. However, they exhibit different responses upon binding suggesting that these two variants are functionally distinct.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for EDNRB/Endothelin R Type B Antibody (NBP1-30599)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: IHC-P, WB.


Filter By Application
IHC-P
(1)
WB
(1)
All Applications
Filter By Species
Human
(1)
Mouse
(1)
All Species

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Video Protocols

WB Video Protocol

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Bioinformatics Tool for EDNRB/Endothelin R Type B Antibody (NBP1-30599)

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Bioinformatics

Gene Symbol EDNRB
Entrez
Uniprot