EDNRB/Endothelin R Type B Products

Antibodies
EDNRB/Endothelin R Type B Ant ...
EDNRB/Endothelin R Type B Antibody
Species: Hu, Ca, Primate
Applications: WB, IHC-P, ICC
Host: Rabbit Polyclonal
EDNRB/Endothelin R Type B Ant ...
EDNRB/Endothelin R Type B Antibody
AF4496
Species: Hu
Applications: WB, Flow, ICC
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
EDNRB/Endothelin R Type B Ant ...
EDNRB/Endothelin R Type B Antibody
NBP1-31108
Species: Hu, Rt, Bv, Canine, Chicken, Mouse, Porcine, Rabbit
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
EDNRB/Endothelin R Type B Ove ...
EDNRB/Endothelin R Type B Overexpr...
NBP2-04148
Applications: WB
EDNRB/Endothelin R Type B Ove ...
EDNRB/Endothelin R Type B Overexpr...
NBP2-11403
Applications: WB
Proteins
EDNRB/Endothelin R Type B Rec ...
EDNRB/Endothelin R Type B Recombin...
H00001910-P01
Species: Hu
Applications: WB, ELISA, PA
EDNRB/Endothelin R Type B Par ...
EDNRB/Endothelin R Type B Partial ...
H00001910-Q01
Species: Hu
Applications: WB, ELISA, PA
EDNRB/Endothelin R Type B Rec ...
EDNRB/Endothelin R Type B Recombin...
NBP2-38136PEP
Species: Hu
Applications: AC
RNAi
EDNRB/Endothelin R Type B RNA ...
EDNRB/Endothelin R Type B RNAi
H00001910-R04
Species: Hu
EDNRB/Endothelin R Type B RNA ...
EDNRB/Endothelin R Type B RNAi
H00001910-R03
Species: Hu

Description

The Endothelin Receptor ETB is expressed in most tissues. Mutations of the receptor gene are responsible for Hirschsprung disease type 2, a multigenic disorder with phenotypes such as bicolored irides, megacolon, hypopigmentation, and hearing loss. The ETB receptor has similar affinity for all three endothelins and activates a phosphatidylinositol-calcium second messenger system. A splice variant, termed SVR, has been described; the sequence of the ETB-SVR receptor is identical to ET-B receptor, with the exception of the intracellular C-terminal domain. While both splice variants bind endothelin ET1, they exhibit different responses, which suggests that they may be functionally distinct. The endothelin B receptor has been reported to be expressed in adrenal, aorta, artery, brain, breast, eye, epididymis, ganglion, heart, kidney, liver, lung, ovary, placenta, prostate, skin, testis, uterus, and vessel. ESTs have been isolated from amnion, B-cell/lung/testis, breast, brain, colon, ear, embryo, eye, heart, kidney, liver, liver/spleen, lung, lymph node, placenta, prostate, and skin libraries.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Mouse
Rat
Product By Gene ID 1910
Alternate Names
  • endothelin B receptor
  • ETRB
  • HSCR
  • ET-BR
  • ETBR
  • ET-B
  • WS4A
  • Endothelin receptor non-selective type
  • HSCR2
  • ETB
  • ABCDS
  • endothelin receptor type B

Research Areas for EDNRB/Endothelin R Type B

Find related products by research area and learn more about each of the different research areas below.

GPCR
Neuroscience
Signal Transduction

PTMs for EDNRB/Endothelin R Type B

Learn more about PTMs related to EDNRB/Endothelin R Type B.

Methylation
Demethylation
Phosphorylation
Reduction
Cleavage

Bioinformatics Tool for EDNRB/Endothelin R Type B

Discover related pathways, diseases and genes to EDNRB/Endothelin R Type B. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.