Dystonin Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: Dystonin Antibody [NBP1-89946] - Staining of human cell line A-431 shows localization to nucleus & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Dystonin Antibody [NBP1-89946] - Staining of human tonsil shows low positivity in non-germinal center cells as expected.
Immunohistochemistry-Paraffin: Dystonin Antibody [NBP1-89946] - Staining of human cerebellum shows weak to moderate cytoplasmic positivity in Purkinje cells.
Immunohistochemistry-Paraffin: Dystonin Antibody [NBP1-89946] - Staining of human kidney shows weak to moderate cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: Dystonin Antibody [NBP1-89946] - Staining of human prostate shows weak to moderate cytoplasmic positivity in smooth muscle cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Dystonin Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: KPRCQNVAEDMDIQLCASILNENSDENENINTMILLDKMHSCSSLEKQQRVNVVQLASPSENNLVTEKSNLPEYTTEIAGKSKENLLNHE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DST
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: PFA/Triton X-100.
Control Peptide
Dystonin Protein (NBP1-89946PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Dystonin Antibody

  • 230 kDa bullous pemphigoid antigen
  • BP240
  • BPAFLJ30627
  • BPAG1FLJ32235
  • Bullous pemphigoid antigen 1
  • bullous pemphigoid antigen 1, 230/240kDa
  • Bullous pemphigoid antigen
  • CATX-15
  • D6S1101
  • DKFZp564B2416
  • DMHCATX15
  • DT
  • Dystonia musculorum protein
  • dystonin
  • FLJ13425
  • FLJ21489
  • FLJ46791
  • Hemidesmosomal plaque protein
  • KIAA0465
  • KIAA0728
  • KIAA1470
  • MACF2
  • trabeculin-beta

Background

Dystonin encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been known that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Dystonin Antibody (NBP1-89946) (0)

There are no publications for Dystonin Antibody (NBP1-89946).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Dystonin Antibody (NBP1-89946) (0)

There are no reviews for Dystonin Antibody (NBP1-89946). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for Dystonin Antibody (NBP1-89946) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Dystonin Products

Research Areas for Dystonin Antibody (NBP1-89946)

Find related products by research area.

Blogs on Dystonin

There are no specific blogs for Dystonin, but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Dystonin Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol DST
Entrez
Uniprot