Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Human Monoclonal
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Dystonin encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been known that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
667 |
| Alternate Names |
- 230 kDa bullous pemphigoid antigen
- BP240
- BPAFLJ30627
- BPAG1FLJ32235
- Bullous pemphigoid antigen 1
- bullous pemphigoid antigen 1, 230/240kDa
- Bullous pemphigoid antigen
- CATX-15
- D6S1101
- DKFZp564B2416
- DMHCATX15
- DT
- Dystonia musculorum protein
- dystonin
- FLJ13425
- FLJ21489
- FLJ46791
- Hemidesmosomal plaque protein
- KIAA0465
- KIAA0728
- KIAA1470
- MACF2
- trabeculin-beta
|
Research Areas for Dystonin
Find related products by research area and learn more about each of the different research areas below.
Cancer
