Dystonin Antibody

Product Discontinued

Dystonin Antibody Summary

• Immunogen: This antibody was made against a protein fragment from the Middle Region
• Specificity: This product is specific for Human DST.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DST
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Microarray
  • Western Blot 1:100 - 1:2000
• Application Notes: Dystonin Antibody validated for Microarray from a verified customer review.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Potassium Phosphate (pH 7.0), 0.15 M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs. These products are available in limited quantities. Please enquire about the availability of this product before purchasing.

Alternate Names for Dystonin Antibody

• 230 kDa bullous pemphigoid antigen
• BP240
• BPAFLJ30627
• BPAG1FLJ32235
• Bullous pemphigoid antigen 1
• bullous pemphigoid antigen 1, 230/240kDa
• Bullous pemphigoid antigen
• CATX-15
• D6S1101
• DKFZp564B2416
• DMHCATX15
• DT
• Dystonia musculorum protein
• dystonin
• FLJ13425
• FLJ21489
• FLJ46791
• Hemidesmosomal plaque protein
• KIAA0465
• KIAA0728
• KIAA1470
• MACF2
• trabeculin-beta

Background

This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been known that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Dystonin Antibody (29720002)(2)

Publications using 29720002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Review for Dystonin Antibody (29720002) (1)

Average Rating: 4

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Carly Garrison MiAr Human 12/05/2019

Summary

• Application: Microarray
• Sample Tested: EDTA Plasma
• Species: Human
• Lot: T000770A01

Bioinformatics

• Gene Symbol: DST
• Uniprot:
  • Q03001(Human)