Dectin-2/CLEC6A Antibody - Azide and BSA Free

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

Dectin-2/CLEC6A Antibody - Azide and BSA Free Summary

• Immunogen: A synthetic peptide from n-terminal region of human Dectin-2/CLEC6A conjugated to an immunogenic carrier protein was used as the antigen.
• Localization: subcellular location: membrane; single-pass type ii membrane protein.; tissue specificity: expressed in dendritic cells.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CLEC6A
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 10-50 ug/ml
  • Immunohistochemistry-Frozen 10-50 ug/ml
  • Immunohistochemistry-Paraffin 10-50 ug/ml
  • Western Blot 10-50 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Ammonium sulfate precipitation
• Reconstitution Instructions: Reconstitute 0.5 mg size in 0.5 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the 0.1 mg size is provided in reconstituted format.

Alternate Names for Dectin-2/CLEC6A Antibody - Azide and BSA Free

• CLEC4N
• CLEC6A
• CLECSF10
• C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 10
• C-type lectin domain family 6 member A
• C-type lectin domain family 6, member A
• C-type lectin superfamily member 10
• DC-associated C-type lectin 2
• dectin 2
• Dectin2
• Dectin-2
• Dendritic cell-associated C-type lectin 2

Background

Dectin 2 is a type II transmembrane protein that is a member of the C type lectin superfamily. In mouse, dectin 2 is predominantly expressed on tissue macrophages and some dendritic cells. Significant expression of Dectin 2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin 2 but transient up regulation of expression has been demonstrated on monocytes at sites of inflammation. The function of dectin 2 has not been fully determined but studies suggest a possible role in immune surveillance.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Dectin-2/CLEC6A Antibody (NBP1-03472)(1)

Publication using NBP1-03472

• Brasch J, Morig A, Neumann B, Proksch E. Expression of antimicrobial peptides and toll-like receptors is increased in tinea and pityriasis versicolor. Mycoses. 2013-08-19 [PMID: 23952012] (IHC-P, Human)

Bioinformatics

• Gene Symbol: CLEC6A
• Entrez:
  • 93978(Human)
• Uniprot:
  • Q6EIG7()