DEC1 Antibody [DyLight 550]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

DEC1 Antibody [DyLight 550] Summary

Immunogen
Synthetic peptide made to a C-terminal region of human DEC1 (between amino acids 350-412) [UniProt O14503]
Localization
Nucleus
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BHLHE40
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Paraffin
Application Notes
This DEC1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western Blot, where a band is seen ~49 kDa. In ICC/IF punctate nuclear staining is observed.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 26834156).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DEC1 Antibody [DyLight 550]

  • basic helix-loop-helix domain containing, class B, 2
  • basic helix-loop-helix family, member e40
  • bHLHb2
  • bHLHe40
  • Class B basic helix-loop-helix protein 2
  • class E basic helix-loop-helix protein 40
  • DEC1HLHB2
  • differentially expressed in chondrocytes 1
  • Differentially expressed in chondrocytes protein 1
  • differentiated embryo chondrocyte expressed gene 1
  • Enhancer-of-split and hairy-related protein 2
  • SHARP2
  • SHARP-2
  • Stimulated by retinoic acid gene 13 protein
  • STRA13FLJ99214
  • Stra14

Background

Differentiated embryo-chondrocyte expressed gene 1 (DEC1) is an important protein involved in embryonic cell differentiation, proliferation, and apoptosis. It has also recently been shown to be regulated by hypoxia. The loss of DEC1 expression may be an early event in the development of lung cancer, while DEC1 may be up-regulated by hypoxia in other cancers and in more extreme hypoxia it may have a role in cell death.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for DEC1 Antibody (NB100-1800R)

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Bioinformatics

Gene Symbol BHLHE40