DAX1/NR0B1 Antibody

Immunohistochemistry-Paraffin: DAX1/NR0B1 Antibody [NB100-59006] - Staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Product Discontinued

DAX1/NR0B1 Antibody Summary

• Immunogen: Synthetic 19 amino acid peptide from ligand-binding domain of human DAX1.
• Epitope: ligand-binding domain of human
• Specificity: Human DAX1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (100%), Primate (95%), Chimpanzee (100%), Orangutan (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NR0B1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
• Control:

  DAX1/NR0B1 Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (95%), Rabbit (84%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for DAX1/NR0B1 Antibody

• AHC
• AHCDSS
• AHCH
• AHX
• DAX1
• DAX1DAX-1
• dosage-sensitive sex reversal
• DSS-AHC critical region on the X chromosome protein 1
• GTD
• HHG
• NR0B1
• NROB1
• nuclear hormone receptor
• Nuclear receptor DAX-1
• nuclear receptor subfamily 0 group B member 1
• nuclear receptor subfamily 0, group B, member 1

Background

This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NR0B1
• Entrez:
  • 190(Human)