Cytosolic Sulfotransferase 2A1/SULT2A1 Antibody (656229) [Alexa Fluor® 647]

• Applications: WB, ICC/IF
• Clone: 656229
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

Cytosolic Sulfotransferase 2A1/SULT2A1 Antibody (656229) [Alexa Fluor® 647] Summary

• Immunogen: E. coli-derived recombinant human Cytosolic Sulfotransferase 2A1/SULT2A1
  Ser2-Glu285
  Accession # NP_003158
• Specificity: Detects human Cytosolic Sulfotransferase 2A1/SULT2A1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human SULT1A1, 1A3, 4A1, 1B1, 2B1, or 1E1 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Sulfotransferase 2A1 (SULT2A1), also called DHEA-ST (DHEA/bile acid sulfotransferase), is a 35 kDa member of the cytosolic sulfotransferase family, which are Phase II drug-metabolizing enzymes that catalyze the sulfation of many endogenous and xenobiotic substrates. SULT2A1 is primarily expressed in liver and adrenal tissues. It sulfates steroids and bile acids, playing roles in maintaining cholesterol and bile acid homeostasis by increasing cholesterol catabolism and preventing toxicity from bile acid accumulation. Human SULT2A1 shares 63-65% amino acid identity with mouse and rat SULT2A1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.