Cytosolic beta-Glucosidase/GBA3 Antibody - Azide and BSA Free

• Reactivity: Hu
• Applications: ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Cytosolic beta-Glucosidase/GBA3 Antibody - Azide and BSA Free Summary

• Description: This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with purified, recombinant Human Cytosolic beta-Glucosidase/GBA3 (Accession#: NP_066024.1; Met 1-Leu 469)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GBA3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:1000-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for Cytosolic beta-Glucosidase/GBA3 Antibody - Azide and BSA Free

• CBG
• CBGL1
• CBGL1GLUC
• Cytosolic betaGlucosidase
• Cytosolic beta-Glucosidase
• Cytosolic beta-glucosidase-like protein 1
• EC 3.2.1.21
• GBA3
• GLUC
• glucosidase, beta, acid 3 (cytosolic)
• klotho-related protein
• KLrP
• MGC104276
• MGC126878

Background

GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GBA3