Cytosolic beta-Glucosidase/GBA3 Products

Description

GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM]

Bioinformatics

Product By Gene ID	57733
Alternate Names	CBG CBGL1 CBGL1GLUC Cytosolic betaGlucosidase Cytosolic beta-Glucosidase Cytosolic beta-glucosidase-like protein 1 EC 3.2.1.21 GBA3 GLUC glucosidase, beta, acid 3 (cytosolic) klotho-related protein KLrP MGC104276 MGC126878