Cortistatin Antibody - BSA Free

Western Blot: Cortistatin Antibody [NBP1-69148] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

• Reactivity: Hu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.5 mg/ml

Cortistatin Antibody - BSA Free Summary

• Description: The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
• Immunogen: Synthetic peptides corresponding to CORT (cortistatin). The peptide sequence was selected from the N terminal of CORT. Peptide sequence is EGGPTGRDSEHMQE and should be able to detect the full-length protein giving a band around ~10-11 kDa.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CORT
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1.0 ug/ml
• Application Notes: Use in ELISA reported in scientific literature (PMID: 30181699).

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 30181699).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, 2% Sucrose
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Affinity purified

Alternate Names for Cortistatin Antibody - BSA Free

• cortistatin
• cortistatin-14
• cortistatin-17
• cortistatin-29
• CST-14
• CST-17
• CST-29
• MGC32686
• preprocortistatin

Background

This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cortistatin Antibody (NBP1-69148)(1)

Publication using NBP1-69148

• Lee B, Shim I, Lee H et al. Tetramethylpyrazine reverses anxiety-like behaviors in a rat model of post-traumatic stress disorder Korean J Physiol Pharmacol 2018-08-29 [PMID: 30181699] (ELISA, Rat)

Bioinformatics

• Gene Symbol: CORT