Reactivity | HuSpecies Glossary |
Applications | WB, ELISA, Flow, IHC, IHC-Fr, IP |
Clone | CS9 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Concentration | 1.0 mg/ml |
Immunogen | Cytochrome B245 solubilised in octyl-beta-gluycopyranoside |
Specificity | This antibody recognises the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterised by severe recurrent infections. |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | CYBA |
Purity | Protein G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Membrane permeabilisation is required for Flow Cytometry. |
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Publications |
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Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer | PBS (pH 7.4) |
Preservative | 0.09% Sodium Azide |
Concentration | 1.0 mg/ml |
Purity | Protein G purified |
Publication using NBP1-40974 | Applications | Species |
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Aurelius J, Hallner A, Werlenius O et al. NOX2-dependent immunosuppression in chronic myelomonocytic leukemia. J. Leukoc. Biol. Mar 14 2017 [PMID: 28292946] (Human) | Human |
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | NBP1-40974AF350 | |
Alexa Fluor 405 | NBP1-40974AF405 | |
Alexa Fluor 488 | NBP1-40974AF488 | |
Alexa Fluor 532 | NBP1-40974AF532 | |
Alexa Fluor 594 | NBP1-40974AF594 | |
Alexa Fluor 647 | NBP1-40974AF647 | |
Alexa Fluor 700 | NBP1-40974AF700 | |
Alexa Fluor 750 | NBP1-40974AF750 | |
Allophycocyanin | NBP1-40974APC | |
Allophycocyanin/Cy7 | NBP1-40974APCCY7 | |
DyLight 350 | NBP1-40974UV | |
DyLight 405 | NBP1-40974V | |
DyLight 488 | NBP1-40974G | |
DyLight 550 | NBP1-40974R | |
DyLight 594 | NBP1-40974DL594 | |
DyLight 650 | NBP1-40974C | |
DyLight 680 | NBP1-40974FR | |
DyLight 755 | NBP1-40974IR | |
Janelia Fluor 549 | NBP1-40974JF549 | |
Janelia Fluor 646 | NBP1-40974JF646 | |
PE | NBP1-40974PE | |
PE/Atto594 | NBP1-40974PEATT594 | |
PE/Cy5.5 | NBP1-40974PECY55 | |
PE/Cy7 | NBP1-40974PECY7 | |
PerCP | NBP1-40974PCP |
Diseases for Cytochrome b245 alpha Antibody (NBP1-40974)Discover more about diseases related to Cytochrome b245 alpha Antibody (NBP1-40974).
| Pathways for Cytochrome b245 alpha Antibody (NBP1-40974)View related products by pathway.
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PTMs for Cytochrome b245 alpha Antibody (NBP1-40974)Learn more about PTMs related to Cytochrome b245 alpha Antibody (NBP1-40974).
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Gene Symbol | CYBA |