Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free [NBP1-02340] - Staining of Human Heart tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

• Reactivity: Hu, Eq, Mu, Pm, Pm
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 amino acid peptide from 1st extracellular domain of human Cysteinyl Leukotriene R2/CysLTR2.
• Epitope: 1st extracellular domain
• Specificity: Human Cysteinyl Leukotriene R2/CysLTR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR109B (59%), OXGR1 (59%), GPR81 (59%).
• Predicted Species: Mouse (94%), Primate (100%), Monkey (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CYSLTR2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 10 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (100%), Gorilla (94%), Panda (94%), Canine (88%), Bovine (88%), Hamster (88%), Elephant (88%), Rabbit (88%), Opossum (88%), Porcine (88%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free

• CysLT(2)
• CysLT2
• CYSLT2KPG_011
• CYSLT2RHG57
• CysLTR2
• cysteinyl leukotriene CysLT2 receptor
• Cysteinyl Leukotriene R2
• cysteinyl leukotriene receptor 2
• Cysteinyl LeukotrieneR2
• G protein-coupled receptor
• G-protein coupled receptor GPCR21
• G-protein coupled receptor HG57
• HG57
• hGPCR21
• HPN321
• KPG_011

Background

Cysteinyl leukotriene receptor 2 (CysLT2) is a Chemoattractant Receptor that binds neutrophil chemoattractants such as cysteinyl leukotrienes. These ligands have potent proinflammatory activity and are implicated in many features of asthma including edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Activation of cysteinyl leukotriene receptor 2 induces cell contraction and/or relaxation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cysteinyl Leukotriene R2/CysLTR2 Antibody (NBP1-02340)(1)

Publication using NBP1-02340

• Brunner SM, Schrödl F, Preishuber-Pflügl J et al. Distribution of the cysteinyl leukotriene system components in the human, rat and mouse eye Experimental eye research 2023-05-19 [PMID: 37211287] (IHC-P, Human)

Bioinformatics

• Gene Symbol: CYSLTR2
• Entrez:
  • 57105(Human)
• Uniprot:
  • Q9NS75(Human)