CYP11A1 Antibody - Azide and BSA Free

Western Blot: CYP11A1 Antibody [H00001583-D01P] - Analysis of CYP11A1 expression in human kidney.

Western Blot: CYP11A1 Antibody [H00001583-D01P] - Analysis of CYP11A1 expression in Jurkat.

Western Blot: CYP11A1 Antibody [H00001583-D01P] - Analysis of CYP11A1 expression in transfected 293T cell line by CYP11A1 polyclonal antibody.Lane 1: CYP11A1 transfected lysate(60.10 KDa).Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CYP11A1 Antibody - Azide and BSA Free Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CYP11A1 (AAH32329.1, 1 a.a. - 521 a.a.) full-length human protein. MLAKGLPPRSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRGILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQQ
• Specificity: Reacts with cytochrome P450, family 11, subfamily A, polypeptide 1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CYP11A1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against tissue and transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CYP11A1 Antibody - Azide and BSA Free

• Cholesterol desmolase
• cholesterol monooxygenase (side-chain-cleaving)
• cholesterol side-chain cleavage enzyme, mitochondrial
• CYPXIA1
• Cytochrome P450 11A1
• Cytochrome P450(scc)
• cytochrome P450, family 11, subfamily A, polypeptide 1
• cytochrome P450C11A1
• EC 1.14.15
• EC 1.14.15.6
• steroid 20-22-lyase
• subfamily XIA (cholesterol side chain cleavage)

Background

CYP11A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP11A1 localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CYP11A1
• Entrez:
  • 1583(Human)
• Uniprot:
  • AAH32329.1(Human)