CTRP2 Antibody

Images

 
Western Blot: CTRP2 Antibody [NBP1-76627] - 3T3 (Balb) cell lysate with CTRP2 (IN) antibody at (A) 1, (B) 2, and (C) 4 ug/ml.
Immunohistochemistry-Paraffin: CTRP2 Antibody [NBP1-76627] - Human brain tissue using CTRP2 antibody at 10 ug/ml.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

CTRP2 Antibody Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide from near the center of human CTRP2. The immunogen is located within amino acids 140 - 190 of CTRP2.
Specificity
These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
C1QTNF2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
CTRP2 polyclonal antibody can be used for the detection of CTRP2 by Western blot at 2 - 4 mg/ml. These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Control Peptide
CTRP2 Peptide (NBP1-76627PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CTRP2 Antibody

  • C1q and tumor necrosis factor related protein 2
  • C1QTNF2
  • complement-c1q tumor necrosis factor-related protein 2
  • CTRP2
  • CTRP2complement C1q tumor necrosis factor-related protein 2
  • zacrp2

Background

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol C1QTNF2
Uniprot