C1qTNF1/CTRP1 Antibody

Images

 
Western Blot: C1qTNF1/CTRP1 Antibody [NBP1-76626] - Analysis of CTRP1 in human kidney cell lysate with CTRP1 (NT) antibody using NBP1-76626 at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry-Paraffin: C1qTNF1/CTRP1 Antibody [NBP1-76626] - Human kidney tissue with CTRP1 antibody at 10 ug/ml.
Immunofluorescence: C1qTNF1/CTRP1 Antibody [NBP1-76626] - Immunofluorescence of CTRP1 in Human Kidney cells with CTRP1 antibody at 20 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC, IHC-P, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

C1qTNF1/CTRP1 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide from near the amino-terminus of human CTRP1. The immunogen is located within amino acids 40 - 90 of CTRP1. Amino Acid Squence: ERAEEQHEKYRPSQD
Specificity
These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
C1QTNF1
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1-2 ug/ml
  • ELISA
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Immunofluorescence 20 ug/ml
Application Notes
These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Control Peptide
C1qTNF1/CTRP1 Peptide (NBP1-76626PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for C1qTNF1/CTRP1 Antibody

  • C1q and tumor necrosis factor related protein 1
  • C1qTNF1
  • CTRP1
  • CTRP1G protein-coupled receptor-interacting protein
  • FLJ90694
  • G protein coupled receptor interacting protein
  • GIPcomplement C1q tumor necrosis factor-related protein 1
  • ZSIG37

Background

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol C1QTNF1
Uniprot