C1qTNF1/CTRP1 Antibody - BSA Free

Western Blot: C1qTNF1/CTRP1 Antibody [NBP1-76626] - Analysis of CTRP1 in human kidney cell lysate with CTRP1 (NT) antibody using NBP1-76626 at (A) 1 and (B) 2 ug/ml.

Immunohistochemistry: C1qTNF1/CTRP1 Antibody - BSA Free [NBP1-76626] - Immunohistochemistry of C1qTNF1/CTRP1 in human kidney tissue with C1qTNF1/CTRP1 antibody at 10 ug/mL.

Immunocytochemistry/ Immunofluorescence: C1qTNF1/CTRP1 Antibody - BSA Free [NBP1-76626] - Immunofluorescence of C1qTNF1/CTRP1 in Human Kidney cells with C1qTNF1/CTRP1 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

C1qTNF1/CTRP1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit C1qTNF1/CTRP1 Antibody - BSA Free (NBP1-76626) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. Anti-C1qTNF1/CTRP1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 15 amino acid synthetic peptide from near the amino-terminus of human CTRP1. The immunogen is located within amino acids 40 - 90 of CTRP1. Amino Acid Squence: ERAEEQHEKYRPSQD
• Specificity: These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: C1QTNF1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 1-2 ug/ml
• Application Notes: Use in ICC/IF reported in scientific literature (PMID:34422821).
• Control Peptide:

  C1qTNF1/CTRP1 Peptide (NBP1-76626PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for C1qTNF1/CTRP1 Antibody - BSA Free

• C1q and tumor necrosis factor related protein 1
• C1qTNF1
• CTRP1
• CTRP1G protein-coupled receptor-interacting protein
• FLJ90694
• G protein coupled receptor interacting protein
• GIPcomplement C1q tumor necrosis factor-related protein 1
• ZSIG37

Background

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for C1qTNF1/CTRP1 Antibody (NBP1-76626)(1)

Publication using NBP1-76626

• Fei H, Xiang P, Luo W Et al. CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway Frontiers in cell and developmental biology 2021-08-04 [PMID: 34422821] (ICC/IF, Rat)

Bioinformatics

• Gene Symbol: C1QTNF1
• Uniprot:
  • NP_940995(Human)