CSDE1 Antibody - BSA Free

Immunoprecipitation: CSDE1 Antibody [NBP1-71914] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-UNR antibody used for IP at 6 mcg/mg lysate. UNR was also immunoprecipitated by rabbit anti-UNR antibodies NBP1-71913 and NBP1-71915, which recognize other epitopes.

• Reactivity: Hu
• Applications: IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

CSDE1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CSDE1 Antibody - BSA Free (NBP1-71914) is a polyclonal antibody validated for use in IP. Anti-CSDE1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen for this product maps to a region between residue 600 and 650 of human Upstream of NRAS using the numbering given in entry NP_001007554.1 (GeneID 7812).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CSDE1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-10 ug/mg lysate
• Application Notes: Western Blot Not recommended

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CSDE1 Antibody - BSA Free

• cold shock domain containing E1, RNA-binding
• cold shock domain-containing protein E1
• D1S155EUNRRP5-1000E10.3
• DKFZp779B0247
• DKFZp779J1455
• FLJ26882
• KIAA0885
• N-ras upstream gene protein
• NRAS-related
• NRU
• Protein UNR
• upstream of NRAS

Background

CSDE1, also known as Cold shock domain-containing protein E1, is a 798 amino acid long isoform that is 89 kDa and a short 767 amino acid isoform that is approx. 86 kDa, which is directly related to the translation of the human rhinovirus RNA as an RNA binding protein. Studies are being performed on the relationship of this protein to chronic lymphocytic leukemia, diamond-blackfan anemia, lymphocytic leukemia, breast cancer, and shock. CSDE1 protein involvement has been observed with relation to PCSK7, SYNCRIP, PABPC1, HNRNPD, PIK3R1 in the regulation of transcription DNA-dependent and male gonad development pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CSDE1 Antibody (NBP1-71914)(1)

Publication using NBP1-71914

• Ray S, Anderson EC. Stimulation of translation by human Unr requires cold shock domains 2 and 4, and correlates with poly(A) binding protein interaction Sci Rep 2016-03-03 [PMID: 26936655] (IP, Human)

Bioinformatics

• Gene Symbol: CSDE1
• Uniprot:
  • NP_001007554.1(Human)