CRMP1 Antibody

Images

 
Western Blot: CRMP1 Antibody [NBP1-76982] - Rat brain tissue lysate with CRMP1 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: CRMP1 Antibody [NBP1-76982] - Immunofluorescence of CRMP1 in mouse brain tissue with CRMP1 antibody at 5 ug/mL.
Immunohistochemistry-Paraffin: CRMP1 Antibody [NBP1-76982] - Mouse brain tissue with CRMP-1 antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Concentration
1 mg/ml

Order Details

CRMP1 Antibody Summary

Immunogen
Antibody was raised against a 18 amino acid peptide from near the amino terminus of human CRMP1.
Clonality
Polyclonal
Host
Rabbit
Gene
CRMP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Conjugate
Unconjugated
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 5 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
CRMP1 Peptide (NBP1-76982PEP)

Reactivity Notes

Human, Mouse, Rat

Alternate Names for CRMP1 Antibody

  • collapsin response mediator protein 1DRP1
  • CRMP-1
  • dihydropyrimidinase-like 1
  • dihydropyrimidinase-related protein 1
  • DPYSL1DRP-1dihydropyrimidinase related protein-1
  • ULIP3
  • ULIP-3
  • Unc-33-like phosphoprotein 3

Background

Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons. This antibody is expected to recognize only the longest isoform of CRMP-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Blogs on CRMP1

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol CRMP1
Uniprot

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