CNTFR Antibody (MM0190-10L29) - Azide and BSA Free

Immunohistochemistry-Paraffin: CNTFR Antibody (MM0190-10L29) [NBP2-12196] - 4% PFA fixed and parffine embedded human placental tissue section (4um) is subjected to IHC staining. Tissue was treated with 15ug/ml Protenase K for antige retrieval before IHC is applied.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: MM0190-10L29
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

CNTFR Antibody (MM0190-10L29) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse CNTFR Antibody (MM0190-10L29) - Azide and BSA Free (NBP2-12196) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human recombinant CNTFR
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Mouse
• Gene: CNTFR
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 15 ug/ml
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for CNTFR Antibody (MM0190-10L29) - Azide and BSA Free

• ciliary neurotrophic factor receptor alpha
• ciliary neurotrophic factor receptor subunit alpha
• ciliary neurotrophic factor receptor
• CNTF receptor subunit alpha
• CNTFR alpha
• CNTFR-alpha
• MGC1774

Background

CNTFR encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CNTFR
• Uniprot:
  • P26992()