CNTFR Products

Antibodies
ELISA Kits
Human CNTFR ELISA Kit (Colori ...
Human CNTFR ELISA Kit (Colorimetric)
NBP3-42382
Species: Hu
Applications: ELISA
Lysates
CNTFR Overexpression Lysate
CNTFR Overexpression Lysate
NBP2-08172
Species: Hu
Applications: WB
Proteins
Recombinant Rat CNTFR His Pro ...
Recombinant Rat CNTFR His Protein
NBP2-53071
Species: Rt
Applications: PAGE
Recombinant Human CNTFR His P ...
Recombinant Human CNTFR His Protein
NBP2-52015
Species: Hu
Applications: PAGE

Description

CNTFR encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 1271
Alternate Names
  • ciliary neurotrophic factor receptor alpha
  • ciliary neurotrophic factor receptor subunit alpha
  • ciliary neurotrophic factor receptor
  • CNTF receptor subunit alpha
  • CNTFR alpha
  • CNTFR-alpha
  • MGC1774

Research Areas for CNTFR

Find related products by research area and learn more about each of the different research areas below.

Growth and Development
Neuronal Cell Markers