CDX2 Antibody

Images

 
Immunohistochemistry-Paraffin: CDX2 Antibody [NB100-2136] - FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-CDX2 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunoprecipitation: CDX2 Antibody [NB100-2136] - Detection of Human CDX2 on HeLa whole cell lysate using NB100-2136. CDX2 was also immunoprecipitated by rabbit anti-CDX2 antibody NB100-2137 using 3 mcg/mg lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P, IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

CDX2 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 250 and 300 of human Caudal Type Homeobox Transcription Factor 2 using the numbering given in entry NP_001256.1 (GeneID 1045).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CDX2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500-1:2000
  • Immunohistochemistry-Paraffin 1:1000
  • Immunoprecipitation 1-4 ug/mg lysate
Application Notes
This antibody is not recommended for Western Blot. Use rabbit anti-CDX2 antibody NB 100-2137.
Control
CDX2 Overexpression Lysate
Reviewed Applications
Read 1 Review rated 5
using
NB100-2136 in the following applications:

Publications
Read Publications using
NB100-2136 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CDX2 Antibody

  • caudal type homeo box transcription factor 2
  • caudal type homeobox 2
  • Caudal-type homeobox protein 2
  • CDX2
  • CDX3
  • CDX-3
  • CDX3caudal type homeobox transcription factor 2
  • homeobox protein CDX-2

Background

CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CDX2 Antibody (NB100-2136)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IHC, IHC-P.


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IHC
(2)
IHC-P
(1)
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Filter By Species
Human
(3)
All Species

Review for CDX2 Antibody (NB100-2136) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NB100-2136:
Filter by Applications
IHC
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry CDX2 NB100-2136
Enlarge
reviewed by:
Anony- mous
IHC Human 04/21/2014
View

Summary

ApplicationImmunohistochemistry
SpeciesHuman
FileView PDF

Product General Protocols

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FAQs for CDX2 Antibody (NB100-2136) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB100-2136AF350
Alexa Fluor 405 NB100-2136AF405
Alexa Fluor 488 NB100-2136AF488
Alexa Fluor 532 NB100-2136AF532
Alexa Fluor 594 NB100-2136AF594
Alexa Fluor 647 NB100-2136AF647
Alexa Fluor 700 NB100-2136AF700
Alexa Fluor 750 NB100-2136AF750
Biotin NB100-2136B
DyLight 350 NB100-2136UV
DyLight 405 NB100-2136V
DyLight 488 NB100-2136G
DyLight 550 NB100-2136R
DyLight 594 NB100-2136DL594
DyLight 650 NB100-2136C
DyLight 680 NB100-2136FR
DyLight 755 NB100-2136IR
FITC NB100-2136F
HRP NB100-2136H
Janelia Fluor 549 NB100-2136JF549
Janelia Fluor 646 NB100-2136JF646

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Blogs on CDX2.

Stemness is responsible for onset and metastasis of colorectal cancer
By Jamshed Arslan, Pharm. D., PhD. Colorectal cancer stem cells are a rare subpopulation of colorectal cancer cells that can self-renew and initiate and sustain tumor growth when transplanted into an animal host.1,2 C...  Read full blog post.

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Contact Information

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Recent Reviews

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1
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Anony- mous
04/21/2014
Application: IHC
Species: Human

Bioinformatics

Gene Symbol CDX2
Entrez
Uniprot
COVID-19 update