Cdx1 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: Cdx1 Antibody [NBP1-49538] - HeLa cells using NBP1-49538. Nuclei (Blue) are counterstained using Hoechst 33258.

Immunohistochemistry: Cdx1 Antibody [NBP1-49538] - Analysis of CDX1 in mouse skin

• Reactivity: Hu, Mu
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.55 mg/ml

Cdx1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Cdx1 Antibody - BSA Free (NBP1-49538) is a polyclonal antibody validated for use in IHC and ICC/IF. Anti-Cdx1 Antibody: Cited in 4 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A genomic peptide made to an internal region of the human Cdx1 protein (within residues 30-150). [Swiss-Prot P47902]
• Localization: Nucleus
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDX1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:200
• Application Notes: This Cdx1 antibody is useful for IHC and ICC.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS and 30% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 0.55 mg/ml
• Purity: Immunogen affinity purified

Notes

Manufactured by Genomic Antibody Technology™. GAT FAQs

Alternate Names for Cdx1 Antibody - BSA Free

• caudal type homeo box transcription factor 1
• caudal type homeobox 1
• caudal type homeobox transcription factor 1
• Caudal-type homeobox protein 1
• caudal-type homeobox protein CDX1
• homeobox protein CDX-1
• MGC116915

Background

The transcription factors Cdx1 and Cdx2 are members of the caudal-related homeobox gene family based on their homology to the factor caudal in Drosophila melanogaster. A wide variety of in vivo and in vitro studies have suggested that Cdx1 and Cdx2 are important in controlling epithelial cell differentiation, proliferation, and function in the intestine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cdx1 Antibody (NBP1-49538)(4)

Publications using NBP1-49538

• Che YH, Choi IY, Song CE et al. Peripheral Neuron-Organoid Interaction Induces Colonic Epithelial Differentiation via Non-Synaptic Substance P Secretion International Journal of Stem Cells 2023-08-30 [PMID: 37385635]
• Douchi D, Yamamura A, Matsuo J et al. A point mutation R122C in RUNX3 promotes the expansion of isthmus stem cells and inhibits their differentiation in the stomach Cellular and molecular gastroenterology and hepatology 2022-01-21 [PMID: 35074568] (IHC-P, Mouse)
• Douchi D, Yamamura A, Matsuo J Et al. Induction of gastric cancer by successive oncogenic activation in the corpus Gastroenterology 2021-08-12 [PMID: 34391772] (ICC/IF, Mouse)
• H Tsujimoto, T Kasahara, SI Sueta, T Araoka, S Sakamoto, C Okada, SI Mae, T Nakajima, N Okamoto, D Taura, M Nasu, T Shimizu, M Ryosaka, Z Li, M Sone, M Ikeya, A Watanabe, K Osafune A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells Cell Rep, 2020-04-07;31(1):107476. 2020-04-07 [PMID: 32268094]

Bioinformatics

• Gene Symbol: CDX1
• Entrez:
  • 1044(Human)
  • 12590(Mouse)
• Uniprot:
  • P47902(Human)
  • P18111(Mouse)