CD7 Antibody (124-1D1) - BSA Free

Flow Cytometry: CD7 Antibody (124-1D1) [NBP3-09123] - Separation of human CD7 positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD7 (124-1D1) purified antibody (concentration in sample 3 ug/ml) GAM APC.

Flow Cytometry: CD7 Antibody (124-1D1) [NBP3-09123] - Surface staining pattern of human peripheral blood stained using anti-human CD7 (124-1D1) purified antibody (concentration in sample 3 ug/ml) GAM APC.

• Reactivity: Hu
• Applications: Flow
• Clone: 124-1D1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CD7 Antibody (124-1D1) - BSA Free Summary

• Additional Information: Clone 124-1D1 was used by HLDA to establish CD designation.
• Immunogen: Human leukocytes
• Specificity: The mouse monoclonal antibody 124-1D1 recognizes an extracellular epitope of CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD7
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1-4 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Phosphate buffered saline (PBS), pH 7.4
• Preservative: 15mM Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for CD7 Antibody (124-1D1) - BSA Free

• CD7 antigen (p41)
• CD7 antigen
• CD7 molecule
• CD7
• GP40T-cell surface antigen Leu-9
• LEU-9
• T-cell antigen CD7
• T-cell leukemia antigen
• Tp40
• TP41
• TP41p41 protein

Background

CD7, also known as gp40, is a 40 kD type I transmembrane glycoprotein member of the immunoglobulin superfamily. It is found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD7