CD45RA Antibody (CA4.1D3)

Images

 
Flow Cytometry: CD45RA Antibody (CA4.1D3) [NB100-64897] - Pan leukocyte detection in Canine IP- whole blood cells. Image courtesy of customer.

Product Details

Summary
Reactivity CaSpecies Glossary
Applications Flow, IHC, IHC-Fr
Clone
CA4.1D3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

CD45RA Antibody (CA4.1D3) Summary

Immunogen
Made to Dog CD45RA
Specificity
Recognizes the canine homologue of CD45RA, a cell surface glycoprotein expressed by B lymphocytes and a subset of T-lymphocytes.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PTPRC
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry Neat
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
Reviewed Applications
Read 1 Review rated 5
using
NB100-64897 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
No buffer
Preservative
0.09% Sodium Azide
Purity
Tissue culture supernatant

Alternate Names for CD45RA Antibody (CA4.1D3)

  • B220
  • CD45 antigen
  • CD45R
  • EC 3.1.3.48
  • L-CA
  • LY5
  • protein tyrosine phosphatase, receptor type, C
  • receptor-type tyrosine-protein phosphatase C
  • T200 glycoprotein
  • T200 leukocyte common antigen
  • T200receptor type, c polypeptide

Background

CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognizing a common epitope on all of the isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Review for CD45RA Antibody (NB100-64897) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Canine.
We have 1 review tested in 1 application: Flow.

Reviews using NB100-64897:
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Images Ratings Applications Species Date Details
Flow Cytometry CD45RA NB100-64897
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reviewed by:
A G
Flow Canine 02/27/2017
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Summary

ApplicationFlow Cytometry
Sample TestedDog whole blood
SpeciesCanine
Lot280812

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CD45RA NB100-64897

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Recent Reviews

5
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1
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A G
02/27/2017
Application: Flow
Species: Canine

Bioinformatics

Gene Symbol PTPRC