CD45RA Antibody (CA4.1D3) - BSA Free

Flow Cytometry: CD45RA Antibody (CA4.1D3) [NB100-64897] - Pan leukocyte detection in Canine IP- whole blood cells. Image courtesy of customer.

• Reactivity: Ca
• Applications: Flow, IHC
• Clone: CA4.1D3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

CD45RA Antibody (CA4.1D3) - BSA Free Summary

• Immunogen: Made to Dog CD45RA
• Specificity: Recognizes the canine homologue of CD45RA, a cell surface glycoprotein expressed by B lymphocytes and a subset of T-lymphocytes.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTPRC
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry Neat
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Tissue culture supernatant
• Preservative: 0.01% Sodium Azide
• Purity: Tissue culture supernatant

Alternate Names for CD45RA Antibody (CA4.1D3) - BSA Free

• B220
• CD45 antigen
• CD45R
• CD45RA
• EC 3.1.3.48
• L-CA
• LY5
• protein tyrosine phosphatase, receptor type, C
• receptor-type tyrosine-protein phosphatase C
• T200 glycoprotein
• T200 leukocyte common antigen
• T200receptor type, c polypeptide

Background

CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognizing a common epitope on all of the isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Review for CD45RA Antibody (NB100-64897) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Canine.

reviewed by: A G Flow Canine 02/27/2017

Summary

• Application: Flow Cytometry
• Sample Tested: Dog whole blood
• Species: Canine
• Lot: 280812

Bioinformatics

• Gene Symbol: PTPRC