CD117/c-kit Antibody (kit2c75) [FITC]

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CD117/c-kit Antibody (kit2c75) [FITC] [NBP1-28328] - Vial of FITC conjugated antibody. FITC is optimally excited at 498 nm by the Blue laser (488 nm) and has an emission maximum of 519 nm.

Product Details

Summary
Reactivity ChSpecies Glossary
Applications Flow, KD
Clone
kit2c75
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

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CD117/c-kit Antibody (kit2c75) [FITC] Summary

Immunogen
Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA)
Marker
Hematopoietic Stem Cell Marker
Specificity
Chicken c-Kit
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KIT
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Knockdown Validated

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for CD117/c-kit Antibody (kit2c75) [FITC]

  • CD117 antigen
  • CD117
  • ckit
  • c-kit
  • EC 2.7.10
  • EC 2.7.10.1
  • KIT
  • PBT
  • piebald trait
  • Proto-oncogene c-Kit
  • proto-oncogene tyrosine-protein kinase Kit
  • SCF R
  • SCFR
  • SCFRmast/stem cell growth factor receptor
  • soluble KIT variant 1
  • Tyrosine-protein kinase Kit
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Background

c-Kit is a 145 kDa transmembrane receptor-type protein tyrosine kinase encoded by the c-Kit protooncogene and is the receptor for stem cell factor (SCF). 1 c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. 2, 3, 4, 5 The amino acid sequence of chicken c-kit shows 63% identity to mouse c-Kit and exhibits similar expression patterns in RNA blot analysis suggesting similar biological roles. (1)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for CD117/c-kit Antibody (NBP1-28328) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for CD117/c-kit Antibody (NBP1-28328)

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Blogs on CD117/c-kit.

Do you see what I see? I c-Kit
The c-Kit (CD117) proto-oncogene is a 145 kD receptor tyrosine kinase family closely related to platelet-derived growth factor receptor (PDGFR). It is a transmembrane receptor and the cellular homolog of the HZ4-feline sarcoma virus transforming gene ...  Read full blog post.

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Bioinformatics

Gene Symbol KIT